Changing Education Paradigm

Dear All,

With regards to the much needed paradigm shift in our education, a talk by Sir Ken Robinson has been animated in the following URL.
Do have a look.


http://www.youtube.com/watch?v=zDZFcDGpL4U

Thanks,
Eshita

Comparing programming languages for bioinformatics

A comparison of common programming languages used in bioinformatics
Mathieu Fourment and Michael R Gillings
BMC Bioinformatics. 2008; 9: 82.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267699/

Nitish Birthday photos

Dear ALL,

Please find the link for Nitish Birthday photos celebration.


https://picasaweb.google.com/108149987886665872224/NitishSBirthday?authuser=0&authkey=Gv1sRgCPas2Zn21IPWMw&feat=directlink

Thanks and Regards,
Sony M

Celebrating 150 hours of teaching

Dear ALL,

Please find the link for group photos attached celebrating the completion of 150 hours of Ma'am's teaching.

https://picasaweb.google.com/108149987886665872224/Celebrating150HoursOfTeaching?authuser=0&authkey=Gv1sRgCK7G-fmZ5_L2_AE&feat=directlink

Thanks and Regards,
Sony M

Agnel's Birthday celebration

Dear ALL,

Please find the link fro Agnel's Birthday celebration.

https://picasaweb.google.com/108149987886665872224/AgnelSBday?authuser=0&authkey=Gv1sRgCLDY6ab3k72RFw&feat=directlink

Thanks and Regards,
Sony M

Malini's Birthday celebration

Dear ALL,

Please find the link for Malini's Birthday celebration photos.

https://picasaweb.google.com/108149987886665872224/MaliniSBday?authuser=0&authkey=Gv1sRgCOfA9_qm_fTrHA&feat=directlink

Thanks and Regards,
Sony M

Prof Janet Thronton's visit

Dear ALL,

Please find the link for group photos with Prof Janet.

https://picasaweb.google.com/108149987886665872224/ProfJanetThorntonSVisit?authuser=0&authkey=Gv1sRgCIHnyKeH9NjXvAE&feat=directlink

Thanks and Regards,
Sony M

Teacher's day celebration photos

Dear ALL,

Please find the link for Teacher's day celebration photos:

https://picasaweb.google.com/108149987886665872224/TeacherSDay?authuser=0&authkey=Gv1sRgCNzuiYP1v_CNVQ&feat=directlink

All the photos look very nice.

Thanks and Regards,
Sony M

Ramanashree Photos

Dear ALL,

Please find the link for Ramanashree Lunch photos:

https://picasaweb.google.com/108149987886665872224/RamanashreePhotos?authuser=0&authkey=Gv1sRgCIicw-_UgNnEfQ&feat=directlink

Thanks and Regards,
Sony M

Ma'am's Birthday celebration

Dear ALL,

Please find the link for Ma'am's Birthday celebration photos:

https://picasaweb.google.com/108149987886665872224/MaAmSBirthday?authuser=0&authkey=Gv1sRgCOGb95_3s5HGogE&feat=directlink

Thanks and Regards,
Sony M

Photos for Nasir's and Anshul's Birthday celebration

Dear ALL,

Please find the link for Nasir and Anshul's Birthday celebration photos.

https://picasaweb.google.com/108149987886665872224/NasirSBirthday?authuser=0&authkey=Gv1sRgCLHTx8e6hP20mwE&feat=directlink

and

https://picasaweb.google.com/108149987886665872224/AnshulSBirthday?authuser=0&authkey=Gv1sRgCP3BvoLQ3LiEUA&feat=directlink


Thanks and Regards,
Sony M

The Illustrated Guide to a Ph.D.

Dear All,

Matthew Might, a computer science professor at the University of Utah, writes: “Every fall, I explain to a fresh batch of Ph.D. students what a Ph.D. is. It’s hard to describe it in words. So, I use pictures.” Here it goes. Matt’s Illustrated Guide:

http://www.openculture.com/2010/09/the_illustrated_guide_to_a_phd.html

banana genome

Dear All
Please see an article in this week's Nature. The draft results are being compared with
Poaceae and species-specific features have been commented upon.
Sowdhamini
 ** The banana (Musa acuminata) genome and the evolution of

monocotyledonous plants
Angelique D'Hont, France Denoeud, Jean-Marc Aury, Franc-Christophe 
Baurens, Francoise Carreel et al.
OPEN
The sequencing and analysis of the banana genome is reported; these 
results inform plant phylogenetic relationships and genome evolution, 
and provide a resource for future genetic improvement of this important 
crop species.
 http://links.ealert.nature.com/ctt?kn=105&ms=Mzk1NjE5MzcS1&r=MjA1NzU2OTA0MAS2&b=2&j=MTUzODYwMTgwS0&mt=1&rt=0

Lab Extension photos

Dear ALL,

The following is the link for lab extension photos..

https://picasaweb.google.com/108149987886665872224/LabExtensionPhotos?authuser=0&authkey=Gv1sRgCMuv-Of_8O-OMg&feat=directlink

Thanks and Regards,
Sony M

genome of 'forgotten ape'

Dear All
In this week's Nature, there is an article about the whole genome sequencing of bonobo and
more than 3% of human genome is found to be similar to bonobo than with chimpanzees.
Sowdhamini

** The bonobo genome compared with the chimpanzee and human genomes
Kay Prufer, Kasper Munch, Ines Hellmann, Keiko Akagi, Jason R. Miller 
et al.
 http://links.ealert.nature.com/ctt?kn=93&ms=MzkzOTEzMzkS1&r=MjA1NzU2OTA0MAS2&b=2&j=MTQ4MzM2MTM2S0&mt=1&rt=0

Lab Day 2012 celebration

Dear ALL,

Please find the link for the lab day celebration..

https://picasaweb.google.com/108149987886665872224/LabDay2012?authuser=0&authkey=Gv1sRgCMuCjOLe_Z_28wE&feat=directlink

They look great :)

Thanks and Regards,
Sony M

Have you taken your vitamins today ?

Dear All
Please see a nice story presented connecting Vitamin K, electron carrier and Parkinson's disease.
Vitamin K2 Is a Mitochondrial Electron Carrier That Rescues Pink1 Deficiency Melissa Vos et al. Adding vitamin K rescues fruit flies bearing a mutation in a Parkinson's disease gene homolog. http://www.sciencemag.org/cgi/content/summary/336/6086/1306 <http://app.aaas-science.org/e/er?s=1906&lid=16944&elq=082c663cc08345e3a3a6a8ac1a556144>
Sowdhamini

avian flu could go airborne!

Dear All
Please see news in Science below. It appears that with as small as three amino acid mutations, avian flu virus could be airborne and spread to mammals without any intermediate host. In this case, we are perhaps glad that there is an eight-month long debate on this possibility !
Sowdhamini

Science 22 June 2012:
Vol. 336 no. 6088 pp. 1494-1497
DOI: 10.1126/science.336.6088.1494

• News & Analysis

Avian Influenza

Public at Last, H5N1 Study Offers Insight Into Virus's Possible Path to Pandemic

1. Martin Enserink*

Summary

Depending on your point of view, the study that appears on page 1534 of this week's issue of Science marks another good week for public health experts trying to protect a vulnerable world from a new influenza pandemic—or for future bioterrorists bent on unleashing one. The paper describes how a handful of mutations might give the H5N1 avian influenza virus, which typically infects birds, the potential to move easily between mammals and touch off a human flu pandemic. It appears after more than 8 months of often fierce international debate over whether the results should be made public—and whether researchers should have conducted the experiments at all.

Lab joining treat

Dear ALL,

Please find the link for the lab joining treat (by Agnel, Anita, Anshul and Malini) photos.
https://picasaweb.google.com/108149987886665872224/LabJoiningTreat?authuser=0&authkey=Gv1sRgCMra-bOG1r_JigE&feat=directlink

Very soon will update more photos at the same link.. Keep a watch :)

Thanks and Regards,
Sony M

Ooty Retreat photos

Dear ALL,

Please find the link for Ooty Retreat photos uploaded on Picasa.

https://picasaweb.google.com/108149987886665872224/OotyRetreat?authuser=0&authkey=Gv1sRgCNKro4a3ltPatAE&feat=directlink

Wonderful photos...

Do have a look.

Thanks and Regards,
Sony M

Wound Healing in Black bears!!!

Dear All,

I am sure you will like this article.
Please visit:
http://www.bbc.co.uk/nature/17404059

Have a Lovely Day ahead..
Best Regards
Anshul..

A Tour of the Cell

 Dear all,

Although the cell is the smallest unit of life, it is by no means simple. The human body is made up of tens of trillions of cells like this one, that have developed a highly synchronized set of components to carry out the processes that keep the organism alive, allow it to reproduce and adapt to changing environments. New research suggests such complex cells, which scientists call eukaryotes, arose from the fusion of two, single-celled organisms in a symbiotic effort to survive. An ostrich egg is the largest known single cell, but most individual cells are too small to see without a microscope.

Please check this link for excellent image,I hope image we never seen  before.

http://www.nsf.gov/news/overviews/biology/interactive.jsp


Thanks & regards,
Mahantesha

How to better our Scientific Communication...

Dear All,

A very good link for getting some insights on "scientific communications". Do visit:

http://www.nature.com/scitable/topic/scientific-communication-14121566

Have a Great Day.. :-)
Best Regards
Anshul..

Swati's Birthday celebration photos

Dear ALL,

The following is the link for Swati's Birthday photos.

https://picasaweb.google.com/108149987886665872224/SwatiSBirthday?authuser=0&authkey=Gv1sRgCNC44oOO78XXeA&feat=directlink

Enjoyy.

Thanks and Regards,
Sony M

Bacterial Evolution Up Close

Dear all,

Two teams explore how a bacterium responds to its environment, offering insight into how the microbes evolve resistance to antibiotics.

Very interesting papers.

Buescher, J., et. al. 2012. Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism. Science. 335: 1099–1103.
2. Nicolas, P., et. al. 2012. Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis. Science. 335: 1103–1106.

Thanks & regards,
Mahantesha

Google water

Do you want to know the link between Google and Chemistry ??? Welcome to the world of Google water. This article talks about how Aurora Clark, Associate Professor of Chemistry at Washington State University, USA, has adapted Google's PageRank software to determine the way molecules are shaped and organized.

Please use this link to read the article fully.
http://www.chemistryviews.org/details/ezine/1494203/.html

crystal structure of UV protector in plants

Dear All
This paper reports the crystal structure of a protein, UVR8, involved in UV protection in Arabidopsis thaliana. Not only the beta-propellor fold is interesting, there is a quarternary switch from homodimer to monomer upon UV exposure. Also, the chemical groups that act as chromophores are two Trp residues.
http://links.ealert.nature.com/ctt?kn=124&ms=Mzg4ODc3MDUS1&r=MjA1NzU2OTA0MAS2&b=2&j=MTMxNjc5OTQ2S0&mt=1&rt=0
Sowdhamini

Sony's Birthday

Dear ALL,

Please find the photos for Sony's birthday celebration.

The following is the link:

https://picasaweb.google.com/108149987886665872224/SonySBirthday02?authuser=0&authkey=Gv1sRgCNSm6I3ntrWyqgE&feat=directlink

Thank you all for the great celebration.

Thanks and Regards,
Sony M

Aurore's Birthday

Dear ALL,

Please find the link for photos for Aurore's birthday celebration.

https://picasaweb.google.com/108149987886665872224/AuroreSBirthday?authuser=0&authkey=Gv1sRgCNa7zZuht5S6eg&feat=directlink

Enjoyyy..

Thanks and Regards,
Sony M

how the deadly toxin is shielded by another protein

Dear All
This article and accompanying paper (by Gu and coworkers) talk about how the deadly botolium neurotoxin is kept protected in the host gastrointestinal tract by another structurally similar protein. All three domains of the two proteins are remarkably similar and they dimerise in a pH dependent manner. Gu and coworkers demonstrate that the mutations of residues at the interchain interface, that form four crucial salt bridges, render them incapable of dimerisation.
URL to the article:
Botulinum neurotoxin must form a complex with a structurally similar protein tosurvive in the gastrointestinal tract. http://www.sciencemag.org/cgi/content/summary/335/6071/928<http://app.aaas-science.org/e/er?s=1906&lid=12360&elq=3b1e5847af4a4432beae97e9ea14fe05>

Sowdhamini

Ancient Genome Sequenced at High-Resolution

Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, David Reich group have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This individual is from a group that shares a common origin with Neanderthals. This population was not involved in the putative gene flow from Neanderthals into Eurasians; however, the data suggest that it contributed 4–6% of its genetic material to the genomes of present-day Melanesians. They designate this hominin population ‘Denisovans’ and suggest that it may have been widespread in Asia during the Late Pleistocene epoch. A tooth found in Denisova Cave carries a mitochondrial genome highly similar to that of the finger bone. This tooth shares no derived morphological features with Neanderthals or modern humans, further indicating that Denisovans have an evolutionary history distinct from Neanderthals and modern humans.

To know more about this please check the link below

http://www.nature.com/nature/journal/v468/n7327/full/nature09710.html

Thanks & regards,

Mahantesha

Why Bad Immunity Genes Survive

Biologists have found new evidence of why mice, people and other vertebrate animals carry thousands of varieties of genes to make immune-system proteins named MHCs--even though some of those genes make vertebrate animals susceptible to infections and to autoimmune diseases.

 Fig.Friend mouse leukemia virus (yellow) budding from infected T-lymphocyte (blue).

To know more about this interesting article please see the link below

http://www.nsf.gov/news/news_summ.jsp?cntn_id=123040&WT.mc_id=USNSF_51&WT.mc_ev=click

Thanks & regards,

Mahantesha 

Anu Nair's Birthday

Dear ALL,

Please find the link for Anu's birthday photos..

They are very nice, dont forget note the difference between before and after photos of Anu. [Before and after FACIAL, I guess Just bake cream works.... ;)]

https://picasaweb.google.com/108149987886665872224/AnuNairSBirthday?authuser=0&authkey=Gv1sRgCPWKqMiB3tXXLA&feat=directlink

Thanks and Regards,
Sony M

dodging the toxic world

Dear All
Although C. elegans is one of the favourite model organisms in the lab, in its real world, it needs to encounter various microbial threats in the soil. One of the threats is a bacterial toxin which some of the strains of this worm learnt to become resistant. Pl. see this commentary and an accompanying paper where Gupta and coworkers have nailed the reason for resistance to few amino acid deletions in a glutamate-gated ion channel. The crystal structure of this protein is also available, but alas we don't know it all - since the crucial deletion region is in the N-terminus and was not included in the crystallisation! But, one could speculate these residues might participate in the ligand-binding pocket.
Surviving in a Toxic World
Adrian J. Wolstenholme Natural variations in a single gene of wild C. elegans populations confer resistanceto the bacterial toxin avermectin. http://www.sciencemag.org/cgi/content/summary/335/6068/545<http://app.aaas-science.org/e/er?s=1906&lid=11674&elq=696c02feff474b108d09a9df581f3761>
has News-and-Views of the same.

Sowdhamini

toxic truth about sugar

Dear All
Sugar is cheap, sugar tastes good, sugar sells, and what is more sugar kills ...
It is found to be as bad as alcohol. Do see this commentary in this week's Science :
** Public health: The toxic truth about sugarAdded sweeteners pose dangers to health that justify controlling them like alcohol, argue Robert H. Lustig, Laura A. Schmidt and Claire D. Brindis. http://links.ealert.nature.com/ctt?kn=102&ms=Mzg3NzcyNTcS1&r=MjA1NzU2OTA0MAS2&b=2&j=MTI4OTczNzM1S0&mt=1&rt=0

Sowdhamini

New Year Celebration with Ethinicity

Dear ALL,

The link for photos for New year celebration is :
https://picasaweb.google.com/108149987886665872224/NewYearCelebrationWithEthinicity?authuser=0&authkey=Gv1sRgCLWDys_WqY7ZywE&feat=directlink

Photos are really nice.

Thanks and Regards,
Sony M