Dear All,
I found a fascinating post on "Why Walking through a Doorway Makes You Forget" .
Read on to discover the mystery behind this very common phenomenon !!
http://www.scientificamerican.com/article.cfm?id=why-walking-through-doorway-makes-you-forget&WT.mc_id=SA_Facebook
Total Pageviews
Thursday, December 15, 2011
Tuesday, November 22, 2011
Visitor to the lab: Jes Frellser
Dear ALL,
Please see the photos of our lab with the visitor Jes Frellser.
https://picasaweb.google.com/108149987886665872224/PhotosWithJesFrellser?authuser=0&authkey=Gv1sRgCKeTwd-rxsahaA&feat=directlink
Thanks and Regards,
Sony M
Please see the photos of our lab with the visitor Jes Frellser.
https://picasaweb.google.com/108149987886665872224/PhotosWithJesFrellser?authuser=0&authkey=Gv1sRgCKeTwd-rxsahaA&feat=directlink
Thanks and Regards,
Sony M
Wednesday, November 16, 2011
Would you like to present your research as a dance !!
'Dance your PhD' contest .... The rules of the contest were simple: Each dance had to be based on a scientist's Ph.D. research, and that scientist had to be part of the dance
http://news.sciencemag.org/sciencenow/2011/10/dance-your-phd-winner-announced.html
So are you ready to "dance your PhD " ??
Cheers,
Eshita
Tuesday, October 18, 2011
Scientists Genetically Engineer Tomatoes with Enhanced Folate Content
Research could provide vital daily nutritional requirement
Scientists have discovered how to enhance tomatoes with folate, an essential nutrient.
Leafy greens and beans aren't the only foods that pack a punch of folate, the vitamin essential for a healthy start to pregnancy.
Researchers now have used genetic engineering--manipulating an organism's genes--to make tomatoes with a full day's worth of the nutrient in a single serving. The scientists published their results in this week's online edition of the journal PNAS, Proceedings of the National Academy of Sciences.
"This could potentially be beneficial worldwide," said Andrew Hanson, a plant biochemist at the University of Florida at Gainesville who developed the tomato along with colleague Jesse Gregory. "Now that we've shown it works in tomatoes, we can work on applying it to cereals and crops for less developed countries where folate deficiencies are a very serious problem."
Folate is one of the most vital nutrients for the human body's growth and development, which is why folate-rich diets are typically suggested for women planning a pregnancy or who are pregnant. Without it, cell division would not be possible because the nutrient plays an essential role in both the production of nucleotides--the building blocks of DNA--and many other essential metabolic processes.
Deficiencies of the nutrient have been linked to birth defects, slow growth rates and other developmental problems in children, as well as numerous health issues in adults, such as anemia.
"Folate deficiency is a major nutritional deficiency, especially in the developing world," said Parag Chitnis, program director in the National Science Foundation's Division of Molecular and Cellular Biosciences, which funded the research. "This research provides the proof-of-concept for the natural addition of folate to diet through enhancement of the folate content of fruits and vegetables."
The vitamin is commonly found in leafy green vegetables like spinach, but few people eat enough produce to get the suggested amount of folate. So, in 1998, the Food and Drug Administration made it mandatory that many grain productssuch as rice, flour and cornmeal be enriched with a synthetic form of folate known as folic acid.
Folate deficiencies remain a problem in many underdeveloped countries, however, where adding folic acid is impractical or simply too expensive.
"There are even folate deficiency issues in Europe, where addition of folic acid to foods has not been very widely practiced," Gregory said. "Theoretically, you could bypass this whole problem by ensuring that the folate is already present in the food."
Will doctors be recommending a healthy dose of salsa for would-be pregnant women anytime soon? Probably not, the researchers say.
"It can take years to get a genetically-engineered food plant approved by the FDA," Hanson said. "But before that is even a question, there are many more studies to be done--including a better look at how the overall product is affected by this alteration."
And there is another hurdle the researchers must clear. Boosting the production of folate in tomatoes involved increasing the level of another chemical in the plant, pteridine. Little is known about this chemical, which is found in virtually all fruits and vegetables.
Thanks & regards,
Mahantesha
Scientists have discovered how to enhance tomatoes with folate, an essential nutrient.
Leafy greens and beans aren't the only foods that pack a punch of folate, the vitamin essential for a healthy start to pregnancy.
Researchers now have used genetic engineering--manipulating an organism's genes--to make tomatoes with a full day's worth of the nutrient in a single serving. The scientists published their results in this week's online edition of the journal PNAS, Proceedings of the National Academy of Sciences.
"This could potentially be beneficial worldwide," said Andrew Hanson, a plant biochemist at the University of Florida at Gainesville who developed the tomato along with colleague Jesse Gregory. "Now that we've shown it works in tomatoes, we can work on applying it to cereals and crops for less developed countries where folate deficiencies are a very serious problem."
Folate is one of the most vital nutrients for the human body's growth and development, which is why folate-rich diets are typically suggested for women planning a pregnancy or who are pregnant. Without it, cell division would not be possible because the nutrient plays an essential role in both the production of nucleotides--the building blocks of DNA--and many other essential metabolic processes.
Deficiencies of the nutrient have been linked to birth defects, slow growth rates and other developmental problems in children, as well as numerous health issues in adults, such as anemia.
"Folate deficiency is a major nutritional deficiency, especially in the developing world," said Parag Chitnis, program director in the National Science Foundation's Division of Molecular and Cellular Biosciences, which funded the research. "This research provides the proof-of-concept for the natural addition of folate to diet through enhancement of the folate content of fruits and vegetables."
The vitamin is commonly found in leafy green vegetables like spinach, but few people eat enough produce to get the suggested amount of folate. So, in 1998, the Food and Drug Administration made it mandatory that many grain productssuch as rice, flour and cornmeal be enriched with a synthetic form of folate known as folic acid.
Folate deficiencies remain a problem in many underdeveloped countries, however, where adding folic acid is impractical or simply too expensive.
"There are even folate deficiency issues in Europe, where addition of folic acid to foods has not been very widely practiced," Gregory said. "Theoretically, you could bypass this whole problem by ensuring that the folate is already present in the food."
Will doctors be recommending a healthy dose of salsa for would-be pregnant women anytime soon? Probably not, the researchers say.
"It can take years to get a genetically-engineered food plant approved by the FDA," Hanson said. "But before that is even a question, there are many more studies to be done--including a better look at how the overall product is affected by this alteration."
And there is another hurdle the researchers must clear. Boosting the production of folate in tomatoes involved increasing the level of another chemical in the plant, pteridine. Little is known about this chemical, which is found in virtually all fruits and vegetables.
Thanks & regards,
Mahantesha
Wednesday, October 12, 2011
Malini's Defense Party at Neel
Dear ALL,
Please find the Malini's Treat photos.
They look nice.
https://picasaweb.google.com/108149987886665872224/MaliniSDefensePartyAtNeel?authuser=0&authkey=Gv1sRgCKeTl5O9taKB6QE&feat=directlink
Enjoyyy
Thanks and Regards,
Sony M
Please find the Malini's Treat photos.
They look nice.
https://picasaweb.google.com/108149987886665872224/MaliniSDefensePartyAtNeel?authuser=0&authkey=Gv1sRgCKeTl5O9taKB6QE&feat=directlink
Enjoyyy
Thanks and Regards,
Sony M
Tuesday, October 4, 2011
Mam's Award photos
Dear All,
Have a look at photos which were taken while mam was receiving the award :)
https://picasaweb.google.com/108149987886665872224/BharatJyotiAwardToMaAm?authuser=0&authkey=Gv1sRgCJ2V6uzto4OgUA&feat=directlink
Thanks and Regards
Sony M
Have a look at photos which were taken while mam was receiving the award :)
https://picasaweb.google.com/108149987886665872224/BharatJyotiAwardToMaAm?authuser=0&authkey=Gv1sRgCJ2V6uzto4OgUA&feat=directlink
Thanks and Regards
Sony M
Thursday, September 22, 2011
Awards for Prof. R. Sowdhamini
Professor of Bioinformatics at NCBS R. Sowdhamini received the Bharat Jyoti Award certificate from the International Friendship Society and the Glory India Gold medal from the Institute of Success Awareness.
GEOFF HYDE
Source: NCBS news
Wednesday, September 14, 2011
Biological data visualization
Please see following link for different methods of biological data visualization:
They have sorted videos according scientific areas.
Friday, September 9, 2011
Ramesha's Solitaire treat
Dear ALL,
The following is the link for Ramesha's treat:
https://picasaweb.google.com/108149987886665872224/RameshaSTreat?authuser=0&authkey=Gv1sRgCP689rqxjJKTXQ&feat=directlink
Thanks and Regards,
Sony M
The following is the link for Ramesha's treat:
https://picasaweb.google.com/108149987886665872224/RameshaSTreat?authuser=0&authkey=Gv1sRgCP689rqxjJKTXQ&feat=directlink
Thanks and Regards,
Sony M
Thursday, September 8, 2011
Online EBI-EMBL Courses!!!
Dear all,
EBI-EMBL started giving online courses in Bioinformatics! No registration fee.
One can train himself/herself at any time he/she likes. Requirement: Good Internet Connection and free time.. :-)
One can train himself/herself at any time he/she likes. Requirement: Good Internet Connection and free time.. :-)
Browse more details at
Best Regards
Anshul..
Anshul..
Thursday, September 1, 2011
Taste stimuli are in discrete regions in the brain
Dear All
Sweet Here, Salty There: Evidence for a Taste Map in the Mammalian Brain
A paper published this week in Science presents a new picture of how taste isencoded in the mouse gustatory cortex, the region of the brain devoted toprocessing taste stimuli.
http://www.sciencemag.org/cgi/content/summary/333/6047/1213[http://app.aaas-science.org/e/er.aspx?s=1906&lid=6794&elq=350bec4c3e3d4bb49af91949db47e384]
Following the finding a decade ago that the localisation of sensors (gustatory receptors) reside in particular parts of the tongue for different types of taste, this paper reports use of optical imaging techniques to detect similar presence of loci in the brain to interpret them.
Sowdhamini
Sweet Here, Salty There: Evidence for a Taste Map in the Mammalian Brain
A paper published this week in Science presents a new picture of how taste isencoded in the mouse gustatory cortex, the region of the brain devoted toprocessing taste stimuli.
http://www.sciencemag.org/cgi/content/summary/333/6047/1213[http://app.aaas-science.org/e/er.aspx?s=1906&lid=6794&elq=350bec4c3e3d4bb49af91949db47e384]
Following the finding a decade ago that the localisation of sensors (gustatory receptors) reside in particular parts of the tongue for different types of taste, this paper reports use of optical imaging techniques to detect similar presence of loci in the brain to interpret them.
Sowdhamini
Wednesday, August 31, 2011
"Non-covalent Interactions"
An untitled artistic photo by Shahar Keinan, postdoctoral research associate, chemistry department, Duke University.
Non-covalent interactions hold the key to understanding many biological and technological problems. Very recently, researchers in the Yang Research Group at Duke introduced a new approach that's based solely on the electron density and its derivatives. The approach enables visualization of the intricate balance of interactions that stabilize a ligand in its active site.
This figure shows the results of the Yang group's new method for the V5X ligand in the active site of HDAC8 protein. Blue indicates strong, attractive interactions; green stands for van der Waals; and red indicates strong, non-bonded overlap. The top-left oval insert (A) shows the van der Waals surface between the ligand and the phenyl ring of Phe139. The top-right oval insert (B) shows the hydrogen bond between the ligand and His140. And the lower-right oval insert (C) shows the stabilization of the Zn2+ ion interaction with the protein and ligand. As a whole, the group's new method clearly highlights how a ligand "fits" the geometry of the active site and the many small contributions that add up to determine the interaction energy between the ligand and protein.
Non-covalent interactions hold the key to understanding many biological and technological problems. Very recently, researchers in the Yang Research Group at Duke introduced a new approach that's based solely on the electron density and its derivatives. The approach enables visualization of the intricate balance of interactions that stabilize a ligand in its active site.
This figure shows the results of the Yang group's new method for the V5X ligand in the active site of HDAC8 protein. Blue indicates strong, attractive interactions; green stands for van der Waals; and red indicates strong, non-bonded overlap. The top-left oval insert (A) shows the van der Waals surface between the ligand and the phenyl ring of Phe139. The top-right oval insert (B) shows the hydrogen bond between the ligand and His140. And the lower-right oval insert (C) shows the stabilization of the Zn2+ ion interaction with the protein and ligand. As a whole, the group's new method clearly highlights how a ligand "fits" the geometry of the active site and the many small contributions that add up to determine the interaction energy between the ligand and protein.
Friday, August 26, 2011
Shameer's Defense
Dear ALL,
The following is the link for treat st Solitaire for Shameer's defence.
https://picasaweb.google.com/108149987886665872224/ShameerSDefense?authuser=0&authkey=Gv1sRgCMT__KnCkMOqGA&feat=directlink
Enjoyy.
Thanks and Regards,
Sony M
Wednesday, August 24, 2011
Ma'am's Birthday
Dear All,
The following is the link for Ma'am's Birthday celebration.
https://picasaweb.google.com/108149987886665872224/MaAmSBirthday?authuser=0&authkey=Gv1sRgCPX589C5kOHtGQ&feat=directlink
Photos are very nice do have a look at them.
Enjoyy
Thanks and Regards,
Sony M
The following is the link for Ma'am's Birthday celebration.
https://picasaweb.google.com/108149987886665872224/MaAmSBirthday?authuser=0&authkey=Gv1sRgCPX589C5kOHtGQ&feat=directlink
Photos are very nice do have a look at them.
Enjoyy
Thanks and Regards,
Sony M
A rare genetic disease where the person borns with *No* Fingerprints!!!
Please visit:
http://news.nationalgeographic.com/news/2011/08/110809-fingerprints-skin-disease-health-science-weird/?source=link_fb20110815fingerprintdisease
Thanks & Best Regards
Anshul..
http://news.nationalgeographic.com/news/2011/08/110809-fingerprints-skin-disease-health-science-weird/?source=link_fb20110815fingerprintdisease
Thanks & Best Regards
Anshul..
Tuesday, August 23, 2011
Friday, August 19, 2011
coral genome revealed by Next Generation Sequencing
Dear All
Please see this week's Nature article reporting the whole genome sequencing of a coral reef.
Apart from the absence of genes to synthesise Cys and the presence of genes to synthesise an unusual amino acid, authors report the presence of enzymes in this genome to produce chemicals that protect against UV radiation.
http://links.ealert.nature.com/ctt?kn=97&ms=MzY5MzcxNzQS1&r=MjA1NzU2OTA0MAS2&b=2&j=MTA5NjU4NjMwS0&mt=1&rt=0
Enjoy!
Sowdhamini
Tuesday, August 16, 2011
New Potent HIV Antibodies
Dear all,
New broadly neutralizing and potent HIV antibodies that mimic CD4 binding from four different donors have been identified.
Check this link.
http://www.rockefeller.edu/labheads/chait/pdf/11/11_Scheid_Science.pdf
Thanks & regards,
Mahantesha Naik B.N.
New broadly neutralizing and potent HIV antibodies that mimic CD4 binding from four different donors have been identified.
“Quite a few of these CD4-binding site antibodies share sequence and structural features, suggesting that the path for the immune system might be fairly restricted, fairly narrow,” said Johannes F. Scheid . Souce: Science Express .
Check this link.
http://www.rockefeller.edu/labheads/chait/pdf/11/11_Scheid_Science.pdf
Thanks & regards,
Mahantesha Naik B.N.
Naseer's and Anshul's B'day
Dear ALL,
Link for Naseer's b'day photos:
https://picasaweb.google.com/108149987886665872224/NaseerSBDay?authuser=0&authkey=Gv1sRgCKWi8bTBoruPsgE&feat=directlink
Link for Anshul's B'day photos:
https://picasaweb.google.com/108149987886665872224/AnshulSBDay?authuser=0&authkey=Gv1sRgCN_Pht3gmrWUygE&feat=directlink
Do check it out.
Enjoy..
Thanks and Regards,
Sony M
Link for Naseer's b'day photos:
https://picasaweb.google.com/108149987886665872224/NaseerSBDay?authuser=0&authkey=Gv1sRgCKWi8bTBoruPsgE&feat=directlink
Link for Anshul's B'day photos:
https://picasaweb.google.com/108149987886665872224/AnshulSBDay?authuser=0&authkey=Gv1sRgCN_Pht3gmrWUygE&feat=directlink
Do check it out.
Enjoy..
Thanks and Regards,
Sony M
Thursday, August 11, 2011
Decoding the stress code
Dear ALL,
An attempt towards decoding the stress code (using comparative genomics), now comparative genomics possible as we have Arabidopsis and also its relative which is adapted to adverse conditions.
One more sequenced genome, very important one, it is of plant Thellungiella parvula. It is an extremophile and is related to Arabidopsis. (nature Genetics)
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.889.html
This genome will be very much useful for studying environmental stress adaptations.
Thanks and Regards,
Sony M
An attempt towards decoding the stress code (using comparative genomics), now comparative genomics possible as we have Arabidopsis and also its relative which is adapted to adverse conditions.
One more sequenced genome, very important one, it is of plant Thellungiella parvula. It is an extremophile and is related to Arabidopsis. (nature Genetics)
http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.889.html
This genome will be very much useful for studying environmental stress adaptations.
Thanks and Regards,
Sony M
Friday, August 5, 2011
Photos link
Dear ALL,
The links for award celebration:
https://picasaweb.google.com/108149987886665872224/BharatJyotiAwardToMaAm?authuser=0&authkey=Gv1sRgCJ2V6uzto4OgUA&feat=directlink
The link for Shameer's thesis celebration:
https://picasaweb.google.com/108149987886665872224/ShameerSThesisDefense?authuser=0&authkey=Gv1sRgCNKxwPiiy8yDNw&feat=directlink
Enjoyy.
Thanks and Regards,
Sony M
The links for award celebration:
https://picasaweb.google.com/108149987886665872224/BharatJyotiAwardToMaAm?authuser=0&authkey=Gv1sRgCJ2V6uzto4OgUA&feat=directlink
The link for Shameer's thesis celebration:
https://picasaweb.google.com/108149987886665872224/ShameerSThesisDefense?authuser=0&authkey=Gv1sRgCNKxwPiiy8yDNw&feat=directlink
Enjoyy.
Thanks and Regards,
Sony M
DNA Caught Rock 'N Rollin': On Rare Occasions DNA Dances Itself Into a Different Shape
ScienceDaily (Jan. 29, 2011) — DNA, that marvelous, twisty molecule of life, has an alter ego, research at the University of Michigan and the University of California, Irvine reveals.
Mahantesha
On rare occasions, its building blocks "rock and roll," deforming the familiar double helix into a different shape.
"We show that the simple DNA double helix exists in an alternative form -- for one percent of the time -- and that this alternative form is functional," said Hashim M. Al-Hashimi, who is the Robert L. Kuczkowski Professor of Chemistry and Professor of Biophysics at U-M. "Together, these data suggest that there are multiple layers of information stored in the genetic code." The findings were published online Jan. 26 in the journal Nature.
It's been known for some time that the DNA molecule can bend and flex, something like a rope ladder, but throughout these gyrations its building blocks -- called bases -- remain paired up just the way they were originally described by James Watson and Francis Crick, who proposed the spiral-staircase structure in 1953. By adapting nuclear magnetic resonance (NMR) technology, Al-Hashimi's group was able to observe transient, alternative forms in which some steps on the stairway come apart and reassemble into stable structures other than the typical Watson-Crick base pairs.
The question was, what were these alternative stable structures?
"Using NMR, we were able to access the chemical shifts of this alternative form," said graduate student Evgenia Nikolova. "These chemical shifts are like fingerprints that tell us something about the structure." Through careful analysis, Nikolova realized the "fingerprints" were typical of an orientation in which certain bases are flipped 180 degrees.
"It's like taking half of the stairway step and flipping it upside down so that the other face now points up," said Al-Hashimi. "If you do this, you can still put the two halves of the step back together, but now what you have is no longer a Watson-Crick base pair; it's something called a Hoogsteen base pair."
"Using computational modeling, we further validated that individual bases can roll over inside the double helix to achieve these Hoogsteen base pairs," said Ioan Andricioaei, an associate professor of chemistry at the University of California, Irvine.
Hoogsteen base pairs have previously been observed in double-stranded DNA, but only when the molecule is bound to proteins or drugs or when the DNA is damaged. The new study shows that even under normal circumstances, with no outside influence, certain sections of DNA tend to briefly morph into the alternative structure, called an "excited state."
Previous studies of DNA structure have relied mainly on techniques such as X-ray and conventional NMR, which can't detect such fleeting or rare structural changes.
"These methods do not capture alternative DNA structural forms that may exist for only a millisecond or in very little abundance, such as one percent of the time," said Al-Hashimi. "We took new solution NMR methods that previously have been used to study rare deformations in proteins and adapted them so that they could be used to study rare states in nucleic acids. Now that we have the right tools to look at these so-called excited states, we may find other short-lived states in DNA and RNA."
Because critical interactions between DNA and proteins are thought to be directed by both the sequence of bases and the flexing of the molecule, these excited states represent a whole new level of information contained in the genetic code, Al-Hashimi said.
In addition to Al-Hashimi, Nikolova and Andricioaei, the paper's authors are undergraduate student Abigail Wise and assistant professor of biological chemistry Patrick O'Brien of U-M and postdoctoral researcher Eunae Kim of the University of California, Irvine.
The researchers received funding from the National Science Foundation, the National Institutes of Health and the University of Michigan.
Thanks & regards
Mahantesha
Tuesday, August 2, 2011
Science of Shopping: Cameras & Software That Track Our Shopping Behavior
Anything possible by software:
Next time you go to a store, take a minute to look at all the things that are trying to grab your attention. With so many products available and so many stores and websites, how do you decide what to buy and where to shop? Whether it's convenience, good service or finding the best deals, store owners want to know what attracts you to their stores, and what it takes to keep you coming back. Turns out, there's a science to all this.
With support from the National Science Foundation (NSF), computer scientists Rajeev Sharma, Satish Mummareddy and their colleagues have developed software that breaks down shopping behavior much like websites do. Sharma's company, VideoMining, uses overhead cameras to put together a top down view of how people shop and what they buy.
"Basically, what VideoMining does is use software along with cameras mounted on the ceiling of stores to track shoppers as they move around the store and create data that helps us understand how shoppers are shopping," explains Sharma. The software creates maps of a store's traffic patterns by digitally analyzing the video. Using the traffic data, VideoMining creates charts and graphs showing well travelled areas in a store and dead spots-–places people ignore. The software also can tabulate how long shoppers take before that "moment of truth" when they select an item to purchase. Cameras are positioned directly above and picture resolution is intentionally set low so all shoppers remain anonymous.
"You cannot identify individual shoppers," says Sharma. "The computer is actually watching the video and generating numbers that represent [each] shopper's behavior. It's all about capturing human behavior so you can really understand it over a long period of time."
The idea is to show retailers and manufacturers the best areas in the store to place products, and how to create a comfortable place for people to shop. "By providing the data to retailers and manufacturers," says Sharma, "they can customize and design the stores and the shelves and the products to match the shoppers' interest."
Sharma identifies trends. For example, people prefer wider aisles when they shop. Women take a lot longer to shop than men, and, except in a few cases, brand loyalty is not always strong. "What we're finding in some categories, people are going to the store and making up their mind right there. You can see people coming in, going between brands and picking up the product based upon price; based upon other attributes."
The software was initially created to monitor the elderly and disabled in their homes. Now it's keeping an eye on shoppers, giving businesses a scientific leg up in the rat race of figuring out how to best serve their customers and keep them coming back.
Thanks & regards,
Mahantesha
Sunday, July 31, 2011
Anupam's Treat Photos
Dear ALL,
The following is the link for Anupam's treat photos:
https://picasaweb.google.com/108149987886665872224/AnupamSTreat?authuser=0&authkey=Gv1sRgCNnm8NqSpJzoswE&feat=directlink
Enjoyy..
Regards,
Sony M
The following is the link for Anupam's treat photos:
https://picasaweb.google.com/108149987886665872224/AnupamSTreat?authuser=0&authkey=Gv1sRgCNnm8NqSpJzoswE&feat=directlink
Enjoyy..
Regards,
Sony M
Friday, July 29, 2011
Turmeric a boon
http://www.molecular-cancer.com/content/10/1/12
Dear ALL,
I came across this interesting article, hope you all will also find it interesting..
Think of any beneficial activity for the body, turmeric has it let it be analgesic, anti inflammatory now anti cancer also.
Popular cancer molecule NF-KB is also targeted by turmeric. Something is there in its stucture and chemistry..
Nature is great..
Please do check blog and get surprised, I have posted the link for this on blog.
Thanks and Regards,
Sony M
Dear ALL,
I came across this interesting article, hope you all will also find it interesting..
Think of any beneficial activity for the body, turmeric has it let it be analgesic, anti inflammatory now anti cancer also.
Popular cancer molecule NF-KB is also targeted by turmeric. Something is there in its stucture and chemistry..
Nature is great..
Please do check blog and get surprised, I have posted the link for this on blog.
Thanks and Regards,
Sony M
Sunday, July 24, 2011
The ultimate web station
Dear all,
Bioinformatics.fr is a web magazine helping bioinformatician or scientists find jobs, conferences, courses, companies and more stuff related to Bioinformatics.. New items are posted daily.
Click here to see CAPS
http://www.bioinformatics.fr/laboratories.php
Computational Approaches to Protein Science (CAPS) National Center for Biological Science, Bangalore, India .
Like this it has lots of option.
To know more about this please check the link below:
http://www.bioinformatics.fr/index.php
Thanks & regards,
Mahantesha
Bioinformatics.fr is a web magazine helping bioinformatician or scientists find jobs, conferences, courses, companies and more stuff related to Bioinformatics.. New items are posted daily.
Click here to see CAPS
http://www.bioinformatics.fr/laboratories.php
Computational Approaches to Protein Science (CAPS) National Center for Biological Science, Bangalore, India .
Like this it has lots of option.
To know more about this please check the link below:
http://www.bioinformatics.fr/index.php
Thanks & regards,
Mahantesha
Sunday, July 17, 2011
Thursday, July 14, 2011
NCBI Database Shut Down Averted
Dear all,
With interim funding from the National Institutes of Health (NIH), the National Center for Biotechnology Information (NCBI) will continue to accept submissions and maintain the Sequence Read Archive (SRA) and Trace Archive repositories.
Earlier this year, the NCBI announced that these repositories for high-throughput sequence data would be discontinued due to budgetary constraints. However, because several large-scale NIH projects depend on SRA and Trace Archive, the NIH has provided funding for these resources until 1 October 2011.
“A small number of large projects dominate the cost for SRA, and the NIH institutes that handle those projects are arranging to either provide direct funding to NCBI for the SRA costs associated with the projects, or they are making alternative arrangements for the data,” NCBI user support representative Monica Romiti told BioTechniques in an e-mail.
In addition, NCBI now plans to continue archiving a subset of next-generation sequencing data after the interim funding expires, including:
In contrast, the NCBI’s international collaborators, the European Molecular Biology Laboratory–European Bioinformatics Institute and the DNA Data Bank of Japan, have restated their plans to continue archiving raw sequencing data for the foreseeable future.
Thanks to interim funding, the National Center for Biotechnology Information’s Sequence Read Archive and Trace Archive databases will continue for now.
With interim funding from the National Institutes of Health (NIH), the National Center for Biotechnology Information (NCBI) will continue to accept submissions and maintain the Sequence Read Archive (SRA) and Trace Archive repositories.
Earlier this year, the NCBI announced that these repositories for high-throughput sequence data would be discontinued due to budgetary constraints. However, because several large-scale NIH projects depend on SRA and Trace Archive, the NIH has provided funding for these resources until 1 October 2011.
“A small number of large projects dominate the cost for SRA, and the NIH institutes that handle those projects are arranging to either provide direct funding to NCBI for the SRA costs associated with the projects, or they are making alternative arrangements for the data,” NCBI user support representative Monica Romiti told BioTechniques in an e-mail.
In addition, NCBI now plans to continue archiving a subset of next-generation sequencing data after the interim funding expires, including:
- RNA-Seq, ChIP-Seq, and epigenomic data submitted to Gene Expression Omnibus (GEO).
- Genomic and transcriptomic assemblies submitted to GenBank.
- 16S Ribosomal RNA data associated with metagenomics submitted to GenBank.
In contrast, the NCBI’s international collaborators, the European Molecular Biology Laboratory–European Bioinformatics Institute and the DNA Data Bank of Japan, have restated their plans to continue archiving raw sequencing data for the foreseeable future.
Monday, July 11, 2011
New Genetic Map of Potato May Lead to Improved Crops
Various types of potatoes that are grown in Peru. These potatoes differ in shape, skin pigmentation and flesh pigmentation.
For more information please check this link.
http://www.nsf.gov/news/news_summ.jsp?cntn_id=120914&WT.mc_id=USNSF_51&WT.mc_ev=click
For more information please check this link.
http://www.nsf.gov/news/news_summ.jsp?cntn_id=120914&WT.mc_id=USNSF_51&WT.mc_ev=click
Tuesday, July 5, 2011
Pfam 25 is out
Dear ALL,
Pfam has released Pfam 25 now.
http://xfam.wordpress.com/2011/04/01/no-seriously-weve-made-a-release/
Now Pfam has 12273 families.
Thanks and Regards,
Sony M
Pfam has released Pfam 25 now.
http://xfam.wordpress.com/2011/04/01/no-seriously-weve-made-a-release/
Now Pfam has 12273 families.
Thanks and Regards,
Sony M
Looking at pathway, not just SNPs
Dear all, Please find the link for "A novel multi-SNP genome-wide association study analysis method identifies pathways affected in disease to provide a systems-level view of disease genomics".
http://www.blogger.com/post-create.g?blogID=3942827382473056314
Thanks and regards,
Mahantesha
http://www.blogger.com/post-create.g?blogID=3942827382473056314
Thanks and regards,
Mahantesha
Sunday, July 3, 2011
Search engine for finding Free full text articles
Dear ALL,
Please find this useful links which is a search engine to find free full text articles:
http://www.freefullpdf.com
Thanks to mam for passing on this useful link.
Keep reading.
Thanks and Regards,
Sony M
Monday, June 27, 2011
Lab Day celebration
Dear ALL,
Please find the link for Lab Day celebration photos.
https://picasaweb.google.com/108149987886665872224/LabDay2011?authkey=Gv1sRgCN-Wm6Dn0YK01gE&feat=directlink
Enjoy,
Thanks and Regards,
Sony M
Please find the link for Lab Day celebration photos.
https://picasaweb.google.com/108149987886665872224/LabDay2011?authkey=Gv1sRgCN-Wm6Dn0YK01gE&feat=directlink
Enjoy,
Thanks and Regards,
Sony M
Kanak's Thesis Defense High tea
Dear ALL,
Please find teh link for Kanaks thesis defense high tea celebration:
https://picasaweb.google.com/108149987886665872224/KanaksThesisDefenseHighTea?authkey=Gv1sRgCIK44_ir_tH2IQ&feat=directlink
Enjoy,
Sony M
Please find teh link for Kanaks thesis defense high tea celebration:
https://picasaweb.google.com/108149987886665872224/KanaksThesisDefenseHighTea?authkey=Gv1sRgCIK44_ir_tH2IQ&feat=directlink
Enjoy,
Sony M
Sunday, June 26, 2011
IMPALA: matching a protein sequence against a collection of PSI-BLAST-constructed position-specific score matrices!!!
Availability: The IMPALA source code, the wolf1187 database, and the
aravind105 database are freely available from the NCBI ftp site
ncbi.nlm.nih.gov. The databases may be found in the subdirectory
ftp://ncbi.nlm.nih.gov/pub/impala . The source code is in
ftp://ncbi.nlm.nih.gov/toolbox/ncbi ˙tools. Some IMPALA executables for
different implementations of UNIX are in ftp://ncbi.nlm.nih.gov/blast/executables .
IMPALA has been added as a search option on the Blocks Database Server
(http://blocks.fhcrc.org/blocks/impala.html)using a library of PSSMs
derived from the BLOCKS database.
aravind105 database are freely available from the NCBI ftp site
ncbi.nlm.nih.gov. The databases may be found in the subdirectory
ftp://ncbi.nlm.nih.gov/pub/
ftp://ncbi.nlm.nih.gov/
different implementations of UNIX are in ftp://ncbi.nlm.nih.gov/blast/
IMPALA has been added as a search option on the Blocks Database Server
(http://blocks.fhcrc.org/
derived from the BLOCKS database.
Tuesday, June 21, 2011
FoldRate: A Web-Server for Predicting Protein Folding Rates from Primary Sequence!!!
www.csbio.sjtu.edu.cn/bioinf/FoldRate/ , by which one can get the
desired result for a query protein sequence in around 30
seconds.
For more detail refer:http://benthamscience.com/open/tobioij/articles/
V003/31TOBIOIJ.pdf
desired result for a query protein sequence in around 30
seconds.
For more detail refer:http://benthamscience.
V003/31TOBIOIJ.pdf
Monday, June 20, 2011
Widespread RNA and DNA Sequence Differences in the Human Transcriptome
Dear all,
A handful of DNA sequences are not transcribed into their cognate RNA sequences, a finding that could overthrow the 50-year-old central dogma of molecular biology.
To know more about this interesting paper, check the attached link below.
http://www.sciencemag.org/content/early/2011/05/18/science.1207018.full.pdf
Thanks,
with regards,
Mahantesha
A handful of DNA sequences are not transcribed into their cognate RNA sequences, a finding that could overthrow the 50-year-old central dogma of molecular biology.
To know more about this interesting paper, check the attached link below.
http://www.sciencemag.org/content/early/2011/05/18/science.1207018.full.pdf
Thanks,
with regards,
Mahantesha
Friday, June 17, 2011
Lab lunch at Saga :17 June 2011
Dear ALL,
Please find the link for photos for lab lunch.
https://picasaweb.google.com/108149987886665872224/LabLunch?authkey=Gv1sRgCMLA2YLz1fu9cQ&feat=directlink
Thanks and Regards,
Sony M
Please find the link for photos for lab lunch.
https://picasaweb.google.com/108149987886665872224/LabLunch?authkey=Gv1sRgCMLA2YLz1fu9cQ&feat=directlink
Thanks and Regards,
Sony M
Thursday, June 16, 2011
Ramesha's and Prashant's Bday
Dear ALL,
Please find the link :
Ramesha's Bday:
https://picasaweb.google.com/108149987886665872224/RameshaSBday?authkey=Gv1sRgCOmM682b5JaPyAE&feat=directlink
Prashant's B'day
https://picasaweb.google.com/108149987886665872224/PrashantSBday?authkey=Gv1sRgCKDJ7_LbjcScxAE&feat=directlink
Enjoy
Sony M
Please find the link :
Ramesha's Bday:
https://picasaweb.google.com/108149987886665872224/RameshaSBday?authkey=Gv1sRgCOmM682b5JaPyAE&feat=directlink
Prashant's B'day
https://picasaweb.google.com/108149987886665872224/PrashantSBday?authkey=Gv1sRgCKDJ7_LbjcScxAE&feat=directlink
Enjoy
Sony M
Sunday, June 12, 2011
Gandhimathi's Bday
Dear ALL,
Link for GM's bday photos..
https://picasaweb.google.com/108149987886665872224/GMSBdayPhotos?authkey=Gv1sRgCJ-DtLSr9OjVxgE&feat=directlink
Cheers,
Sony M
Link for GM's bday photos..
https://picasaweb.google.com/108149987886665872224/GMSBdayPhotos?authkey=Gv1sRgCJ-DtLSr9OjVxgE&feat=directlink
Cheers,
Sony M
Tuesday, June 7, 2011
Kannan and Eshita's Bdays.
Dear ALL,
Please find the links for photos for Kannan's and Eshita's birthdays.
https://picasaweb.google.com/108149987886665872224/KannanSBDay?authkey=Gv1sRgCKujiM7i4KGszgE&feat=directlink
https://picasaweb.google.com/108149987886665872224/EshitaSBDay?authkey=Gv1sRgCMjL8Iy9kKPaKQ&feat=directlink
Enjoyy.
Regards.
Sony M
Please find the links for photos for Kannan's and Eshita's birthdays.
https://picasaweb.google.com/108149987886665872224/KannanSBDay?authkey=Gv1sRgCKujiM7i4KGszgE&feat=directlink
https://picasaweb.google.com/108149987886665872224/EshitaSBDay?authkey=Gv1sRgCMjL8Iy9kKPaKQ&feat=directlink
Enjoyy.
Regards.
Sony M
Thursday, March 31, 2011
PhD education in India !!!!!!!
Dear All,
I came across following interesting article on "PhD education in India" and want to share it with all.
http://www.indiaeducationreview.com/article/today%E2%80%99s-phd-education-india-aiming-create-inspiring-intellectual-leaders-tomorrow
I came across following interesting article on "PhD education in India" and want to share it with all.
http://www.indiaeducationreview.com/article/today%E2%80%99s-phd-education-india-aiming-create-inspiring-intellectual-leaders-tomorrow
Monday, March 14, 2011
One and only B'day in march
Dear ALL,
Watch the photos of one and only B'day in March...
https://picasaweb.google.com/108149987886665872224/SwatiSBday?authkey=Gv1sRgCLKSr6Lar4_zvwE&feat=directlink
Sony M
Watch the photos of one and only B'day in March...
https://picasaweb.google.com/108149987886665872224/SwatiSBday?authkey=Gv1sRgCLKSr6Lar4_zvwE&feat=directlink
Sony M
Sunday, February 27, 2011
Anupam's and Sony's Birthday
Dear ALL,
Please check Birthday Photos :-)
1. Anupam's Birthday
https://picasaweb.google.com/108149987886665872224/AnupamSBirthday?authkey=Gv1sRgCLuDvNDCx8izFQ&feat=directlink
2. Sony's Birthday
https://picasaweb.google.com/108149987886665872224/SonySBirthday?authkey=Gv1sRgCOmWpeahjrXWKg&feat=directlink
Thanks and Regards,
Sony M
Please check Birthday Photos :-)
1. Anupam's Birthday
https://picasaweb.google.com/108149987886665872224/AnupamSBirthday?authkey=Gv1sRgCLuDvNDCx8izFQ&feat=directlink
2. Sony's Birthday
https://picasaweb.google.com/108149987886665872224/SonySBirthday?authkey=Gv1sRgCOmWpeahjrXWKg&feat=directlink
Thanks and Regards,
Sony M
Thursday, February 24, 2011
When You Write Your Essays in Programming Languages
Hello All,
Check out this funny link about what happens when we "When You Write Your Essays in Programming Languages"
http://imgur.com/ZyeCO
:)
Check out this funny link about what happens when we "When You Write Your Essays in Programming Languages"
http://imgur.com/ZyeCO
:)
Monday, February 21, 2011
Sridhar's B'day Photos
Dear ALL,
Please check Sridhar's birthday photos:
https://picasaweb.google.com/108149987886665872224/SridharSBDay?authkey=Gv1sRgCMCJh6KKiveW3QE&feat=directlink
Enjoy,
Sony M
Please check Sridhar's birthday photos:
https://picasaweb.google.com/108149987886665872224/SridharSBDay?authkey=Gv1sRgCMCJh6KKiveW3QE&feat=directlink
Enjoy,
Sony M
Friday, February 11, 2011
New Gadget
Dear ALL,
144
Dont get scared by seeeing this up on the blog, it is displaying the number of visits to our blog :-)
Sony M
Dont get scared by seeeing this up on the blog, it is displaying the number of visits to our blog :-)
Sony M
Thursday, February 10, 2011
Some more photos :-)
Its Party time :-)
1. Kanaks thesis submission party @Sanjeevnam
https://picasaweb.google.com/108149987886665872224/Sanjeevnam?authkey=Gv1sRgCJ6cr9aVo7jveA&feat=directlink
Some photos from Sridhar's camera:
Thanks Sridhar
2. Anu Nair's Birthday celebration:
https://picasaweb.google.com/108149987886665872224/AnuNairSBirthdayCelebration?authkey=Gv1sRgCOnk66Gg6dr9ew&feat=directlink
3. Adwait's Birthday celebration:
https://picasaweb.google.com/108149987886665872224/AdwaitSBirthday?authkey=Gv1sRgCNejl9e8qpLIBg&feat=directlink
Enjoy...
Sony M
1. Kanaks thesis submission party @Sanjeevnam
https://picasaweb.google.com/108149987886665872224/Sanjeevnam?authkey=Gv1sRgCJ6cr9aVo7jveA&feat=directlink
Some photos from Sridhar's camera:
https://picasaweb.google.com/107844782442337714025/Sanjeevanam?authkey=Gv1sRgCOn01JCHkKy6XQ&feat=directlink Thanks Sridhar
2. Anu Nair's Birthday celebration:
https://picasaweb.google.com/108149987886665872224/AnuNairSBirthdayCelebration?authkey=Gv1sRgCOnk66Gg6dr9ew&feat=directlink
3. Adwait's Birthday celebration:
https://picasaweb.google.com/108149987886665872224/AdwaitSBirthday?authkey=Gv1sRgCNejl9e8qpLIBg&feat=directlink
Enjoy...
Sony M
Curation generation
Katherine Sanderson in a NatureJobs feature talks about the generation of Biocuration .... With biological databases growing in size and number, curators are needed to update and correct their contents. For those who prefer computers to pipettes, there are opportunities.
Check this news at :
http://www.nature.com/naturejobs/2011/110210/full/nj7333-295a.html
Check this news at :
http://www.nature.com/naturejobs/2011/110210/full/nj7333-295a.html
Photos link
Dear All,
Please follow the links to photos uploaded at Picasa for lab events. We will be updating the albums soon.
1. HFSP Award:
https://picasaweb.google.com/108149987886665872224/HFSPAward?authkey=Gv1sRgCIbsqPOGptfVNw&feat=directlink
2. INSA lunch:
https://picasaweb.google.com/108149987886665872224/INSALunch?authkey=Gv1sRgCLuTvvq014CcGw&feat=directlink
3. Review Meeting:
https://picasaweb.google.com/108149987886665872224/AnnualReviewMeeting?authkey=Gv1sRgCIaj8cvPjpfqyQE&feat=directlink
4. NCBS Best Student award:
https://picasaweb.google.com/108149987886665872224/NCBSBestStudentAward?authkey=Gv1sRgCOnl9t7huomVtgE&feat=directlink
Thanks,
Sony M
Please follow the links to photos uploaded at Picasa for lab events. We will be updating the albums soon.
1. HFSP Award:
https://picasaweb.google.com/108149987886665872224/HFSPAward?authkey=Gv1sRgCIbsqPOGptfVNw&feat=directlink
2. INSA lunch:
https://picasaweb.google.com/108149987886665872224/INSALunch?authkey=Gv1sRgCLuTvvq014CcGw&feat=directlink
3. Review Meeting:
https://picasaweb.google.com/108149987886665872224/AnnualReviewMeeting?authkey=Gv1sRgCIaj8cvPjpfqyQE&feat=directlink
4. NCBS Best Student award:
https://picasaweb.google.com/108149987886665872224/NCBSBestStudentAward?authkey=Gv1sRgCOnl9t7huomVtgE&feat=directlink
Thanks,
Sony M
Tuesday, February 8, 2011
Monday, February 7, 2011
Lab mates are accepting the invitations
Hey guys ,
Nice to see to you all on our blog page, please contribute to posts at the blog and do feel free to drop your suggestions :)
Nice to see to you all on our blog page, please contribute to posts at the blog and do feel free to drop your suggestions :)
Tuesday, January 25, 2011
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