Toll receptor structure with and without ligand

Dear All
This paper, appeared in this week's SCIENCE, is interesting to us. Please go through.

Structural Reorganization of the Toll-Like Receptor 8 Dimer Induced by
Agonistic
Ligands
<http://app.aaas-science.org/e/er?s=1906&lid=28421&elq=448e95072b734b69843f6df8b11412e9>

Hiromi Tanji et al.

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The crystal structure of unbound and ligand-bound Toll-like receptor 8
reveals
ligand-induced conformational changes.

Sowdhamini