LATEST ONLINE ** Computational biology: A recipe for ligand-binding proteins Giovanna Ghirlanda http://links.ealert.nature.com/ctt?kn=72&ms=NDI0ODk4NjcS1&r=MjA1NzU2OTA0MAS2&b=2&j=MjAxNzU0NjA1S0&mt=1&rt=0
Please read main article as well. Sowdhamini
Pallava Bagla and Richard Stone <?xml version="1.0"?> With 400 million people earning less than $1.25 per day, India is home to a staggering one-third of the world's poor. Can scientists do more to lift people out of poverty? A Role for Science in Poverty Alleviation? <http://app.aaas-science.org/e/er?s=1906&lid=31117&elq=4cf94d6aa4ae43a8a50359b7eb150246>
Sowdhamini
--Biological Sciences -The genomes of four tapeworm species reveal adaptations to parasitism Existing treatments for tapeworms are not always reliable and some have adverse side effects, so new drugs are urgently needed. The publication of four tapeworm genome sequences — human-infective species Echinococcus multilocularis, E. granulosus, Taenia solium and the laboratory model Hymenolepis microstoma — and the identification of potential new drug targets for treating tapeworm infections is therefore a welcome development. More than a thousand E. multilocularis proteins emerge as potential targets, and of these, close to 200 may be targeted by existing pharmaceuticals.
http://links.ealert.nature.com/ctt?kn=91&ms=NDEyNjA5MjIS1&r=MjA1NzU2OTA0MAS2&b=2&j=MTgzNTM0MTg1S0&mt=1&rt=0
** Draft genome of the wheat A-genome progenitor Triticum urartu Hong-Qing Ling, Shancen Zhao, Dongcheng Liu et al. The genome sequence and its analysis of the diploid wild wheat Triticum urartu (progenitor of the wheat A genome) represent a tool for studying the complex, polyploid wheat genomes and should be a valuable resource for the genetic improvement of wheat. http://links.ealert.nature.com/ctt?kn=106&ms=NDEyNjA5MjIS1&r=MjA1NzU2OTA0MAS2&b=2&j=MTgzNTM0MTg1S0&mt=1&rt=0 ** Aegilops tauschii draft genome sequence reveals a gene repertoire for wheat adaptation Jizeng Jia, Shancen Zhao, Xiuying Kong et al. OPEN Sequencing and analysing the diploid genome and transcriptome of Aegilops tauschii provide new insights into the role of this genome in enabling the adaptation of bread wheat and are a step towards understanding the very large and complicated hexaploid genomes of wheat species. http://links.ealert.nature.com/ctt?kn=105&ms=NDEyNjA5MjIS1&r=MjA1NzU2OTA0MAS2&b=2&j=MTgzNTM0MTg1S0&mt=1&rt=0
Structural Reorganization of the Toll-Like Receptor 8 Dimer Induced by Agonistic Ligands <http://app.aaas-science.org/e/er?s=1906&lid=28421&elq=448e95072b734b69843f6df8b11412e9> Hiromi Tanji et al. <?xml version="1.0"?> The crystal structure of unbound and ligand-bound Toll-like receptor 8 reveals ligand-induced conformational changes.
